1-(3-CHLOROPHENYL)-4-(3-CHLOROPROPYL)PIPERAZINE HCl

PRODUCT IDENTIFICATION

CAS NO. 39577-43-0

1-(3-CHLOROPHENYL)-4-(3-CHLOROPROPYL)PIPERAZINE HYDROCHLORIDE

EINECS NO. 254-529-9
FORMULA C13H18Cl2N2.HCl
MOL WT. 309.67

H.S. CODE

 

TOXICITY

 

SYNONYMS Chlorure de 1-(3-Chlorophényl)-4-(3-chloropropyl)pipérazine;
Cloruro de 1-(3-Clorofenil)-4-(3-cloropropil)piperazina;
SMILES  

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to off-white crystalline powder

MELTING POINT

199 - 204 C

BOILING POINT

 

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SOLUBILITY IN WATER

 

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AUTOIGNITION

 

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REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS

Piperazine is a heterocyclic compound containing four carbon atoms and two of nitrogen at 1,4 position ( als called 1,4-hexahydropyrazine). It is a deliquescent crystalline compound melting at 105 C; soluble in water, alcohol, glycerol, and glycols. It is used as a main ingredient of anthelmintics used to treat intestinal roundworms (ascariasis) infection in human and  poultry and to treat pinworms (enterobiasis; oxyuriasis) by altering cell membrane permeability and causing hyperpolarization of the membrane. Piperazine is a main moiety in psychoactive drugs. Certain piperazine derivatives are suspected of ecstasy substitutes. Benzylpiperazine is bannaed in many countries. Benzylpiperazine  has been used as a anthelmintic (antiparastic effect). Nitrogen in piperazine ring plays an important role in biological research and drug manufacturing industry including the preparation of anthelmintic, antiallergenic, antibacterial, antihistamic, antiemetic and antimigraine agents. The piperazine ring and piperazine derivatives are important cyclic components in industrial field as raw materials for hardener of epoxy resins, corrosion inhibitors, insecticides, accelerators for rubber, urethane catalysts and antioxidants. An Examples of target compound from 1-(3-Chlorophenyl)-4-(3-chloropropyl) piperazine are antidepressant agents ( etoperidone, nefazodone, trazodone).
SALES SPECIFICATION

APPEARANCE

white to yellowish crystalline powder
PURITY

98.0% min

WATER

0.5% min

TRANSPORTATION
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OTHER INFORMATION

Hazard Symbols: XN, Risk Phrases: 20/21/22, Safety Phrases: 24/25